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        "hgvsWellDefined": "XP_011544248.1:p.[Phe608_Leu609del;Ile611_Phe614del;Leu616_Pro623delinsTyrHisArg;Lys625_Lys630del;Cys632_Pro636del;Glu638Thr]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS556315"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 2788,
          "referenceAllele": "TT",
          "start": 2786
        }
      ],
      "gene": "http://reg.genome.network/gene/GN026144",
      "geneNCBI_id": 79728,
      "geneSymbol": "PALB2",
      "hgvs": [
        "XM_011545947.2:c.1823_1824del"
      ],
      "proteinEffect": {
        "hgvs": "XP_011544249.1:p.Phe608SerfsTer10",
        "hgvsWellDefined": "XP_011544249.1:p.[Phe608_Leu609del;Ile611_Phe614del;Leu616_Pro623delinsTyrHisArg;Lys625_Lys630del;Cys632_Pro636del;Glu638Thr]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS556316"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 2110,
          "referenceAllele": "TT",
          "start": 2108
        }
      ],
      "gene": "http://reg.genome.network/gene/GN026144",
      "geneNCBI_id": 79728,
      "geneSymbol": "PALB2",
      "hgvs": [
        "XM_011545948.2:c.932_933del"
      ],
      "proteinEffect": {
        "hgvs": "XP_011544250.1:p.Phe311SerfsTer10",
        "hgvsWellDefined": "XP_011544250.1:p.[Phe311_Leu312del;Ile314_Phe317del;Leu319_Pro326delinsTyrHisArg;Lys328_Lys333del;Cys335_Pro339del;Glu341Thr]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS556317"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 2788,
          "referenceAllele": "TT",
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        }
      ],
      "gene": "http://reg.genome.network/gene/GN026144",
      "geneNCBI_id": 79728,
      "geneSymbol": "PALB2",
      "hgvs": [
        "XM_017023671.1:c.1823_1824del"
      ],
      "proteinEffect": {
        "hgvs": "XP_016879160.1:p.Phe608SerfsTer10",
        "hgvsWellDefined": "XP_016879160.1:p.[Phe608_Leu609del;Ile611_Phe614del;Leu616_Pro623delinsTyrHisArg;Lys625_Lys630del;Cys632_Pro636del;Glu638Thr]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS574393"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1998,
          "referenceAllele": "TT",
          "start": 1996
        }
      ],
      "gene": "http://reg.genome.network/gene/GN026144",
      "geneNCBI_id": 79728,
      "geneSymbol": "PALB2",
      "hgvs": [
        "XM_017023672.2:c.1817_1818del"
      ],
      "proteinEffect": {
        "hgvs": "XP_016879161.1:p.Phe606SerfsTer10",
        "hgvsWellDefined": "XP_016879161.1:p.[Phe606_Leu607del;Ile609_Phe612del;Leu614_Pro621delinsTyrHisArg;Lys623_Lys628del;Cys630_Pro634del;Glu636Thr]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS574394"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1998,
          "referenceAllele": "TT",
          "start": 1996
        }
      ],
      "gene": "http://reg.genome.network/gene/GN026144",
      "geneNCBI_id": 79728,
      "geneSymbol": "PALB2",
      "hgvs": [
        "XM_017023673.2:c.1817_1818del"
      ],
      "proteinEffect": {
        "hgvs": "XP_016879162.1:p.Phe606SerfsTer10",
        "hgvsWellDefined": "XP_016879162.1:p.[Phe606_Leu607del;Ile609_Phe612del;Leu614_Pro621delinsTyrHisArg;Lys623_Lys628del;Cys630_Pro634del;Glu636Thr]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS574395"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1971,
          "referenceAllele": "TT",
          "start": 1969
        }
      ],
      "gene": "http://reg.genome.network/gene/GN026144",
      "geneNCBI_id": 79728,
      "geneSymbol": "PALB2",
      "hgvs": [
        "NM_024675.4:c.1817_1818del"
      ],
      "proteinEffect": {
        "hgvs": "NP_078951.2:p.Phe606SerfsTer10",
        "hgvsWellDefined": "NP_078951.2:p.[Phe606_Leu607del;Ile609_Phe612del;Leu614_Pro621delinsTyrHisArg;Lys623_Lys628del;Cys630_Pro634del;Glu636Thr]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS698739",
      "MANE": {
        "maneVersion": "1.3",
        "maneStatus": "MANE Select",
        "nucleotide": {
          "Ensembl": {
            "hgvs": "ENST00000261584.9:c.1817_1818del"
          },
          "RefSeq": {
            "hgvs": "NM_024675.4:c.1817_1818del"
          }
        },
        "protein": {
          "Ensembl": {
            "hgvs": "ENSP00000261584.4:p.Phe606SerfsTer10"
          },
          "RefSeq": {
            "hgvs": "NP_078951.2:p.Phe606SerfsTer10"
          }
        }
      }
    }
  ],
  "type": "nucleotide"
}