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      "geneSymbol": "LDLR",
      "hgvs": [
        "NM_001195798.2:c.1529del"
      ],
      "proteinEffect": {
        "hgvs": "NP_001182727.1:p.Thr510SerfsTer?",
        "hgvsWellDefined": "NP_001182727.1:p.[Thr510_Lys518delinsSerTyrSerGlyArgThrAla;Arg520_Gly529delinsSerGlnGlyProSerTrpTrpIleLeu;Tyr532_Trp533delinsAlaSerCys;Asp535_Trp536delinsGlyLeuThr;Thr538delinsGluLeu]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS679343"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1492,
          "referenceAllele": "C",
          "start": 1491
        }
      ],
      "gene": "http://reg.genome.network/gene/GN006547",
      "geneNCBI_id": 3949,
      "geneSymbol": "LDLR",
      "hgvs": [
        "NM_001195799.2:c.1406del"
      ],
      "proteinEffect": {
        "hgvs": "NP_001182728.1:p.Thr469SerfsTer?",
        "hgvsWellDefined": "NP_001182728.1:p.[Thr469_Lys477delinsSerTyrSerGlyArgThrAla;Arg479_Gly488delinsSerGlnGlyProSerTrpTrpIleLeu;Tyr491_Trp492delinsAlaSerCys;Asp494_Trp495delinsGlyLeuThr;Thr497delinsGluLeu]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS679344"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1111,
          "referenceAllele": "C",
          "start": 1110
        }
      ],
      "gene": "http://reg.genome.network/gene/GN006547",
      "geneNCBI_id": 3949,
      "geneSymbol": "LDLR",
      "hgvs": [
        "NM_001195800.2:c.1025del"
      ],
      "proteinEffect": {
        "hgvs": "NP_001182729.1:p.Thr342SerfsTer?",
        "hgvsWellDefined": "NP_001182729.1:p.[Thr342_Lys350delinsSerTyrSerGlyArgThrAla;Arg352_Gly361delinsSerGlnGlyProSerTrpTrpIleLeu;Tyr364_Trp365delinsAlaSerCys;Asp367_Trp368delinsGlyLeuThr;Thr370delinsGluLeu]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS679345"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1234,
          "referenceAllele": "C",
          "start": 1233
        }
      ],
      "gene": "http://reg.genome.network/gene/GN006547",
      "geneNCBI_id": 3949,
      "geneSymbol": "LDLR",
      "hgvs": [
        "NM_001195803.2:c.1148del"
      ],
      "proteinEffect": {
        "hgvs": "NP_001182732.1:p.Thr383SerfsTer?",
        "hgvsWellDefined": "NP_001182732.1:p.[Thr383_Lys391delinsSerTyrSerGlyArgThrAla;Arg393_Gly402delinsSerGlnGlyProSerTrpTrpIleLeu;Tyr405_Trp406delinsAlaSerCys;Asp408_Trp409delinsGlyLeuThr;Thr411delinsGluLeu]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS679346"
    }
  ],
  "type": "nucleotide"
}