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      },
      "referenceSequence": "http://reg.genome.network/refseq/RS681492"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 945,
          "endIntronDirection": "+",
          "endIntronOffset": 19152,
          "referenceAllele": "A",
          "start": 945,
          "startIntronDirection": "+",
          "startIntronOffset": 19151
        }
      ],
      "gene": "http://reg.genome.network/gene/GN010472",
      "geneNCBI_id": 860,
      "geneSymbol": "RUNX2",
      "hgvs": [
        "NM_001369405.1:c.643+19152A>C"
      ],
      "proteinEffect": {
        "hgvs": "NP_001356334.1:n.643+19152A>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS691630"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 882,
          "endIntronDirection": "+",
          "endIntronOffset": 19152,
          "referenceAllele": "A",
          "start": 882,
          "startIntronDirection": "+",
          "startIntronOffset": 19151
        }
      ],
      "gene": "http://reg.genome.network/gene/GN010472",
      "geneNCBI_id": 860,
      "geneSymbol": "RUNX2",
      "hgvs": [
        "NM_001015051.4:c.685+19152A>C"
      ],
      "proteinEffect": {
        "hgvs": "NP_001015051.3:n.685+19152A>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS711368"
    }
  ],
  "type": "nucleotide"
}