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          "endIntronDirection": "+",
          "endIntronOffset": 3,
          "referenceAllele": "A",
          "start": 1493,
          "startIntronDirection": "+",
          "startIntronOffset": 2
        }
      ],
      "gene": "http://reg.genome.network/gene/GN011187",
      "geneNCBI_id": 6654,
      "geneSymbol": "SOS1",
      "hgvs": [
        "NM_005633.4:c.864+3A>G"
      ],
      "proteinEffect": {
        "hgvs": "NP_005624.2:n.864+3A>G"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS727653",
      "MANE": {
        "maneVersion": "1.3",
        "maneStatus": "MANE Select",
        "nucleotide": {
          "Ensembl": {
            "hgvs": "ENST00000402219.8:c.864+3A>G"
          },
          "RefSeq": {
            "hgvs": "NM_005633.4:c.864+3A>G"
          }
        },
        "protein": {
          "Ensembl": {
            "hgvs": "ENSP00000384675.2:n.864+3A>G"
          },
          "RefSeq": {
            "hgvs": "NP_005624.2:n.864+3A>G"
          }
        }
      }
    }
  ],
  "type": "nucleotide"
}