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      "proteinEffect": {
        "hgvs": "NP_001350457.1:p.Pro1175LeufsTer?",
        "hgvsWellDefined": "NP_001350457.1:p.[Pro1175_Met1183delinsLeuSerProArgThrSerThrThrCys;Leu1185_Glu1187delinsCysArgSerCys;Leu1188_Ser1189insThrPro;Asn1190_Ala1191delinsTrpArg;Met1193Ser;Ala1195_Glu1196delinsSer;Phe1198_Thr1204delinsSerThrGlyThrGln]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS720739"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 3634,
          "referenceAllele": "C",
          "start": 3633
        }
      ],
      "gene": "http://reg.genome.network/gene/GN012363",
      "geneNCBI_id": 7249,
      "geneSymbol": "TSC2",
      "hgvs": [
        "NM_021055.3:c.3524del"
      ],
      "proteinEffect": {
        "hgvs": "NP_066399.2:p.Pro1175LeufsTer?",
        "hgvsWellDefined": "NP_066399.2:p.[Pro1175_Met1183delinsLeuSerProArgThrSerThrThrCys;Leu1185_Glu1187delinsCysArgSerCys;Leu1188_Ser1189insThrPro;Asn1190_Ala1191delinsTrpArg;Met1193Ser;Ala1195_Glu1196delinsSer;Phe1198_Thr1204delinsSerThrGlyThrGln]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS728502"
    }
  ],
  "type": "nucleotide"
}