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        {
          "allele": "",
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          "referenceAllele": "T",
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      "gene": "http://reg.genome.network/gene/GN026144",
      "geneNCBI_id": 79728,
      "geneSymbol": "PALB2",
      "hgvs": [
        "XM_011545948.2:c.2540del"
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      "proteinEffect": {
        "hgvs": "XP_011544250.1:p.Leu847TyrfsTer21",
        "hgvsWellDefined": "XP_011544250.1:p.[Leu847_Ala854delinsTyrPheSerValSerVal;Leu856del;Pro858_Val859delinsSer;Asp861_Gln862del;Trp864Leu;Phe866_Ser870delinsLeuThrAsnIle;Thr872_His875delinsLeu]"
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      "referenceSequence": "http://reg.genome.network/refseq/RS556317"
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      "gene": "http://reg.genome.network/gene/GN026144",
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      "geneSymbol": "PALB2",
      "hgvs": [
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      "proteinEffect": {
        "hgvs": "XP_016879160.1:p.Leu1065TyrfsTer21",
        "hgvsWellDefined": "XP_016879160.1:p.[Leu1065_Ala1072delinsTyrPheSerValSerVal;Leu1074del;Pro1076_Val1077delinsSer;Asp1079_Gln1080del;Trp1082Leu;Phe1084_Ser1088delinsLeuThrAsnIle;Thr1090_His1093delinsLeu]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS574393"
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      "coordinates": [
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      "gene": "http://reg.genome.network/gene/GN026144",
      "geneNCBI_id": 79728,
      "geneSymbol": "PALB2",
      "hgvs": [
        "XM_017023672.2:c.3188del"
      ],
      "proteinEffect": {
        "hgvs": "XP_016879161.1:p.Leu1063TyrfsTer21",
        "hgvsWellDefined": "XP_016879161.1:p.[Leu1063_Ala1070delinsTyrPheSerValSerVal;Leu1072del;Pro1074_Val1075delinsSer;Asp1077_Gln1078del;Trp1080Leu;Phe1082_Ser1086delinsLeuThrAsnIle;Thr1088_His1091delinsLeu]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS574394"
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    {
      "coordinates": [
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      "gene": "http://reg.genome.network/gene/GN026144",
      "geneNCBI_id": 79728,
      "geneSymbol": "PALB2",
      "hgvs": [
        "XM_017023673.2:c.*60del"
      ],
      "proteinEffect": {
        "hgvs": "XP_016879162.1:n.*60del"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS574395"
    },
    {
      "coordinates": [
        {
          "allele": "",
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          "referenceAllele": "T",
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      "gene": "http://reg.genome.network/gene/GN026144",
      "geneNCBI_id": 79728,
      "geneSymbol": "PALB2",
      "hgvs": [
        "NM_024675.4:c.3425del"
      ],
      "proteinEffect": {
        "hgvs": "NP_078951.2:p.Leu1142TyrfsTer21",
        "hgvsWellDefined": "NP_078951.2:p.[Leu1142_Ala1149delinsTyrPheSerValSerVal;Leu1151del;Pro1153_Val1154delinsSer;Asp1156_Gln1157del;Trp1159Leu;Phe1161_Ser1165delinsLeuThrAsnIle;Thr1167_His1170delinsLeu]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS698739",
      "MANE": {
        "maneVersion": "1.3",
        "maneStatus": "MANE Select",
        "nucleotide": {
          "Ensembl": {
            "hgvs": "ENST00000261584.9:c.3425del"
          },
          "RefSeq": {
            "hgvs": "NM_024675.4:c.3425del"
          }
        },
        "protein": {
          "Ensembl": {
            "hgvs": "ENSP00000261584.4:p.Leu1142TyrfsTer21"
          },
          "RefSeq": {
            "hgvs": "NP_078951.2:p.Leu1142TyrfsTer21"
          }
        }
      }
    }
  ],
  "type": "nucleotide"
}