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      "proteinEffect": {
        "hgvs": "NP_001161221.1:n.184-8T>G"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS678543"
    },
    {
      "coordinates": [
        {
          "allele": "G",
          "end": 896,
          "endIntronDirection": "-",
          "endIntronOffset": 7,
          "referenceAllele": "T",
          "start": 896,
          "startIntronDirection": "-",
          "startIntronOffset": 8
        }
      ],
      "gene": "http://reg.genome.network/gene/GN021285",
      "geneNCBI_id": 55811,
      "geneSymbol": "ADCY10",
      "hgvs": [
        "NM_001297772.2:c.367-8T>G"
      ],
      "proteinEffect": {
        "hgvs": "NP_001284701.1:n.367-8T>G"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS683137"
    },
    {
      "coordinates": [
        {
          "allele": "G",
          "end": 859,
          "endIntronDirection": "-",
          "endIntronOffset": 7,
          "referenceAllele": "T",
          "start": 859,
          "startIntronDirection": "-",
          "startIntronOffset": 8
        }
      ],
      "gene": "http://reg.genome.network/gene/GN021285",
      "geneNCBI_id": 55811,
      "geneSymbol": "ADCY10",
      "hgvs": [
        "NM_018417.6:c.643-8T>G"
      ],
      "proteinEffect": {
        "hgvs": "NP_060887.2:n.643-8T>G"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS698037",
      "MANE": {
        "maneVersion": "1.3",
        "maneStatus": "MANE Select",
        "nucleotide": {
          "Ensembl": {
            "hgvs": "ENST00000367851.9:c.643-8T>G"
          },
          "RefSeq": {
            "hgvs": "NM_018417.6:c.643-8T>G"
          }
        },
        "protein": {
          "Ensembl": {
            "hgvs": "ENSP00000356825.4:n.643-8T>G"
          },
          "RefSeq": {
            "hgvs": "NP_060887.2:n.643-8T>G"
          }
        }
      }
    }
  ],
  "type": "nucleotide"
}