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      "referenceSequence": "http://reg.genome.network/refseq/RS567255"
    },
    {
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        {
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          "end": 2457,
          "referenceAllele": "AGCTGTGGCGCTGGAAACCTGCAACC",
          "start": 2431
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        "hgvsWellDefined": "XP_016869722.1:p.[Ala663_Val664delinsPro;Glu667_Thr668delinsPro;Asn670_Pro671del;Pro673_Ala676delinsValGlyGlyVal;Trp678_Pro683delinsAlaGlnLeuMetHisIle;Ser685_Thr687delinsTrpTrp;Ala689_Gly690delinsArgPro;Ala692Leu;Leu694_Leu696del;Asn698_Thr700delinsArgAsp]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS567256"
    },
    {
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        {
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          "referenceAllele": "AGCTGTGGCGCTGGAAACCTGCAACC",
          "start": 1619
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      "gene": "http://reg.genome.network/gene/GN001366",
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      "hgvs": [
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      ],
      "proteinEffect": {
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        "hgvsWellDefined": "XP_016869723.1:p.[Ala463_Val464delinsPro;Glu467_Thr468delinsPro;Asn470_Pro471del;Pro473_Ala476delinsValGlyGlyVal;Trp478_Pro483delinsAlaGlnLeuMetHisIle;Ser485_Thr487delinsTrpTrp;Ala489_Gly490delinsArgPro;Ala492Leu;Leu494_Leu496del;Asn498_Thr500delinsArgAsp]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS567257"
    },
    {
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        {
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          "end": 3459,
          "endIntronDirection": "+",
          "endIntronOffset": 799,
          "referenceAllele": "AGCTGTGGCGCTGGAAACCTGCAACC",
          "start": 3459,
          "startIntronDirection": "+",
          "startIntronOffset": 773
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      "gene": "http://reg.genome.network/gene/GN001366",
      "geneNCBI_id": 11093,
      "geneSymbol": "ADAMTS13",
      "hgvs": [
        "XM_017014235.1:c.2234+774_2234+799del"
      ],
      "proteinEffect": {
        "hgvs": "XP_016869724.1:n.2234+774_2234+799del"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS567258"
    },
    {
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          "endIntronDirection": "-",
          "endIntronOffset": 1320,
          "referenceAllele": "AGCTGTGGCGCTGGAAACCTGCAACC",
          "start": 3193,
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          "startIntronOffset": 1346
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      ],
      "gene": "http://reg.genome.network/gene/GN001366",
      "geneNCBI_id": 11093,
      "geneSymbol": "ADAMTS13",
      "hgvs": [
        "XR_001746171.1:n.3194-1346_3194-1321del"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS594527"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 2385,
          "referenceAllele": "AGCTGTGGCGCTGGAAACCTGCAACC",
          "start": 2359
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      ],
      "gene": "http://reg.genome.network/gene/GN001366",
      "geneNCBI_id": 11093,
      "geneSymbol": "ADAMTS13",
      "hgvs": [
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      ],
      "proteinEffect": {
        "hgvs": "NP_620595.1:p.Ala762ProfsTer?",
        "hgvsWellDefined": "NP_620595.1:p.[Ala762_Val763delinsPro;Glu766_Thr767delinsPro;Asn769_Pro770del;Pro772_Ala775delinsValGlyGlyVal;Trp777_Pro782delinsAlaGlnLeuMetHisIle;Ser784_Thr786delinsTrpTrp;Ala788_Gly789delinsArgPro;Ala791Leu;Leu793_Leu795del;Asn797_Thr799delinsArgAsp]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS699826"
    },
    {
      "coordinates": [
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          "referenceAllele": "AGCTGTGGCGCTGGAAACCTGCAACC",
          "start": 2452
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      ],
      "gene": "http://reg.genome.network/gene/GN001366",
      "geneNCBI_id": 11093,
      "geneSymbol": "ADAMTS13",
      "hgvs": [
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      "proteinEffect": {
        "hgvs": "NP_620596.2:p.Ala793ProfsTer?",
        "hgvsWellDefined": "NP_620596.2:p.[Ala793_Val794delinsPro;Glu797_Thr798delinsPro;Asn800_Pro801del;Pro803_Ala806delinsValGlyGlyVal;Trp808_Pro813delinsAlaGlnLeuMetHisIle;Ser815_Thr817delinsTrpTrp;Ala819_Gly820delinsArgPro;Ala822Leu;Leu824_Leu826del;Asn828_Thr830delinsArgAsp]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS699827"
    },
    {
      "coordinates": [
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          "end": 2478,
          "referenceAllele": "AGCTGTGGCGCTGGAAACCTGCAACC",
          "start": 2452
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      ],
      "gene": "http://reg.genome.network/gene/GN001366",
      "geneNCBI_id": 11093,
      "geneSymbol": "ADAMTS13",
      "hgvs": [
        "NM_139025.5:c.2376_2401del"
      ],
      "proteinEffect": {
        "hgvs": "NP_620594.1:p.Ala793ProfsTer?",
        "hgvsWellDefined": "NP_620594.1:p.[Ala793_Val794delinsPro;Glu797_Thr798delinsPro;Asn800_Pro801del;Pro803_Ala806delinsValGlyGlyVal;Trp808_Pro813delinsAlaGlnLeuMetHisIle;Ser815_Thr817delinsTrpTrp;Ala819_Gly820delinsArgPro;Ala822Leu;Leu824_Leu826del;Asn828_Thr830delinsArgAsp]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS729201"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 2385,
          "referenceAllele": "AGCTGTGGCGCTGGAAACCTGCAACC",
          "start": 2359
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      ],
      "gene": "http://reg.genome.network/gene/GN001366",
      "geneNCBI_id": 11093,
      "geneSymbol": "ADAMTS13",
      "hgvs": [
        "NM_139026.6:c.2283_2308del"
      ],
      "proteinEffect": {
        "hgvs": "NP_620595.1:p.Ala762ProfsTer?",
        "hgvsWellDefined": "NP_620595.1:p.[Ala762_Val763delinsPro;Glu766_Thr767delinsPro;Asn769_Pro770del;Pro772_Ala775delinsValGlyGlyVal;Trp777_Pro782delinsAlaGlnLeuMetHisIle;Ser784_Thr786delinsTrpTrp;Ala788_Gly789delinsArgPro;Ala791Leu;Leu793_Leu795del;Asn797_Thr799delinsArgAsp]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS729202"
    },
    {
      "coordinates": [
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          "allele": "",
          "end": 2478,
          "referenceAllele": "AGCTGTGGCGCTGGAAACCTGCAACC",
          "start": 2452
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      ],
      "gene": "http://reg.genome.network/gene/GN001366",
      "geneNCBI_id": 11093,
      "geneSymbol": "ADAMTS13",
      "hgvs": [
        "NM_139027.6:c.2376_2401del"
      ],
      "proteinEffect": {
        "hgvs": "NP_620596.2:p.Ala793ProfsTer?",
        "hgvsWellDefined": "NP_620596.2:p.[Ala793_Val794delinsPro;Glu797_Thr798delinsPro;Asn800_Pro801del;Pro803_Ala806delinsValGlyGlyVal;Trp808_Pro813delinsAlaGlnLeuMetHisIle;Ser815_Thr817delinsTrpTrp;Ala819_Gly820delinsArgPro;Ala822Leu;Leu824_Leu826del;Asn828_Thr830delinsArgAsp]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS729203",
      "MANE": {
        "maneVersion": "1.3",
        "maneStatus": "MANE Select",
        "nucleotide": {
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          "RefSeq": {
            "hgvs": "NM_139027.6:c.2376_2401del"
          }
        },
        "protein": {
          "Ensembl": {
            "hgvs": "ENSP00000347927.2:p.Ala793ProfsTer?"
          },
          "RefSeq": {
            "hgvs": "NP_620596.2:p.Ala793ProfsTer?"
          }
        }
      }
    },
    {
      "coordinates": [
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      "referenceSequence": "http://reg.genome.network/refseq/RS730190"
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  "type": "nucleotide"
}