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      "proteinEffect": {
        "hgvs": "NP_001005735.1:p.Glu282Ter",
        "hgvsWellDefined": "NP_001005735.1:p.Glu282_Leu586delinsArgLysThrCysLysLysValAlaIleLysIleIleSerLysArgLysPheAlaIleGlySerAlaArgGluAlaAspProAlaLeuAsnValGluThrGluIleGluIleLeuLysLysLeuAsnHisProCysIleIleLysIleLysAsnPhePheAspAlaGluAspTyrTyrIleValLeuGluLeuMetGluGlyGlyGluLeuPheAspLysValValGlyAsnLysArgLeuLysGluAlaThrCysLysLeuTyrPheTyrGlnMetLeuLeuAlaValGlnTyrLeuHisGluAsnGlyIleIleHisArgAspLeuLysProGluAsnValLeuLeuSerSerGlnGluGluAspCysLeuIleLysIleThrAspPheGlyHisSerLysIleLeuGlyGluThrSerLeuMetArgThrLeuCysGlyThrProThrTyrLeuAlaProGluValLeuValSerValGlyThrAlaGlyTyrAsnArgAlaValAspCysTrpSerLeuGlyValIleLeuPheIleCysLeuSerGlyTyrProProPheSerGluHisArgThrGlnValSerLeuLysAspGlnIleThrSerGlyLysTyrAsnPheIleProGluValTrpAlaGluValSerGluLysAlaLeuAspLeuValLysLysLeuLeuValValAspProLysAlaArgPheThrThrGluGluAlaLeuArgHisProTrpLeuGlnAspGluAspMetLysArgLysPheGlnAspLeuLeuSerGluGluAsnGluSerThrAlaLeuProGlnValLeuAlaGlnProSerThrSerArgLysArgProArgGluGlyGluAlaGluGlyAlaGluThrThrLysArgProAlaValCysAlaAlaValLeuTer"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS675207"
    },
    {
      "@id": "http://reg.genome.network/allele/PA2826444363",
      "coordinates": [
        {
          "allele": "T",
          "end": 887,
          "referenceAllele": "G",
          "start": 886
        }
      ],
      "gene": "http://reg.genome.network/gene/GN016627",
      "geneNCBI_id": 11200,
      "geneSymbol": "CHEK2",
      "hgvs": [
        "NM_001257387.2:c.52G>T"
      ],
      "proteinEffect": {
        "hgvs": "NP_001244316.1:p.Glu18Ter",
        "hgvsWellDefined": "NP_001244316.1:p.Glu18_Leu322delinsArgLysThrCysLysLysValAlaIleLysIleIleSerLysArgLysPheAlaIleGlySerAlaArgGluAlaAspProAlaLeuAsnValGluThrGluIleGluIleLeuLysLysLeuAsnHisProCysIleIleLysIleLysAsnPhePheAspAlaGluAspTyrTyrIleValLeuGluLeuMetGluGlyGlyGluLeuPheAspLysValValGlyAsnLysArgLeuLysGluAlaThrCysLysLeuTyrPheTyrGlnMetLeuLeuAlaValGlnTyrLeuHisGluAsnGlyIleIleHisArgAspLeuLysProGluAsnValLeuLeuSerSerGlnGluGluAspCysLeuIleLysIleThrAspPheGlyHisSerLysIleLeuGlyGluThrSerLeuMetArgThrLeuCysGlyThrProThrTyrLeuAlaProGluValLeuValSerValGlyThrAlaGlyTyrAsnArgAlaValAspCysTrpSerLeuGlyValIleLeuPheIleCysLeuSerGlyTyrProProPheSerGluHisArgThrGlnValSerLeuLysAspGlnIleThrSerGlyLysTyrAsnPheIleProGluValTrpAlaGluValSerGluLysAlaLeuAspLeuValLysLysLeuLeuValValAspProLysAlaArgPheThrThrGluGluAlaLeuArgHisProTrpLeuGlnAspGluAspMetLysArgLysPheGlnAspLeuLeuSerGluGluAsnGluSerThrAlaLeuProGlnValLeuAlaGlnProSerThrSerArgLysArgProArgGluGlyGluAlaGluGlyAlaGluThrThrLysArgProAlaValCysAlaAlaValLeuTer"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS680730"
    },
    {
      "@id": "http://reg.genome.network/allele/PA2827475453",
      "coordinates": [
        {
          "allele": "T",
          "end": 572,
          "referenceAllele": "G",
          "start": 571
        }
      ],
      "gene": "http://reg.genome.network/gene/GN016627",
      "geneNCBI_id": 11200,
      "geneSymbol": "CHEK2",
      "hgvs": [
        "NM_001349956.2:c.514G>T"
      ],
      "proteinEffect": {
        "hgvs": "NP_001336885.1:p.Glu172Ter",
        "hgvsWellDefined": "NP_001336885.1:p.Glu172_Leu476delinsArgLysThrCysLysLysValAlaIleLysIleIleSerLysArgLysPheAlaIleGlySerAlaArgGluAlaAspProAlaLeuAsnValGluThrGluIleGluIleLeuLysLysLeuAsnHisProCysIleIleLysIleLysAsnPhePheAspAlaGluAspTyrTyrIleValLeuGluLeuMetGluGlyGlyGluLeuPheAspLysValValGlyAsnLysArgLeuLysGluAlaThrCysLysLeuTyrPheTyrGlnMetLeuLeuAlaValGlnTyrLeuHisGluAsnGlyIleIleHisArgAspLeuLysProGluAsnValLeuLeuSerSerGlnGluGluAspCysLeuIleLysIleThrAspPheGlyHisSerLysIleLeuGlyGluThrSerLeuMetArgThrLeuCysGlyThrProThrTyrLeuAlaProGluValLeuValSerValGlyThrAlaGlyTyrAsnArgAlaValAspCysTrpSerLeuGlyValIleLeuPheIleCysLeuSerGlyTyrProProPheSerGluHisArgThrGlnValSerLeuLysAspGlnIleThrSerGlyLysTyrAsnPheIleProGluValTrpAlaGluValSerGluLysAlaLeuAspLeuValLysLysLeuLeuValValAspProLysAlaArgPheThrThrGluGluAlaLeuArgHisProTrpLeuGlnAspGluAspMetLysArgLysPheGlnAspLeuLeuSerGluGluAsnGluSerThrAlaLeuProGlnValLeuAlaGlnProSerThrSerArgLysArgProArgGluGlyGluAlaGluGlyAlaGluThrThrLysArgProAlaValCysAlaAlaValLeuTer"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS688142"
    }
  ],
  "type": "nucleotide"
}