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        "hgvsWellDefined": "XP_011539533.1:p.[Ile141_Gly145delinsSerTrpThrLys;Leu147_Gln152delinsProCysSerGlyProCys;Gly154_Ala160delinsLeuAlaSerValProGly;Asp162_Pro169delinsHisTrpThrCysLeuArgLysSer;Arg170_Asp171insHis]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS108174"
    },
    {
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        {
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          "referenceAllele": "G",
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      ],
      "gene": "http://reg.genome.network/gene/GN008923",
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      "geneSymbol": "PHGDH",
      "hgvs": [
        "XM_011541226.2:c.936del"
      ],
      "proteinEffect": {
        "hgvs": "XP_011539528.1:p.Ile313SerfsTer?",
        "hgvsWellDefined": "XP_011539528.1:p.[Ile313_Gly317delinsSerTrpThrLys;Leu319_Gln324delinsProCysSerGlyProCys;Gly326_Ala332delinsLeuAlaSerValProGly;Asp334_Pro341delinsHisTrpThrCysLeuArgLysSer;Arg342_Asp343insHis]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS554356"
    },
    {
      "coordinates": [
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          "start": 926
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      ],
      "gene": "http://reg.genome.network/gene/GN008923",
      "geneNCBI_id": 26227,
      "geneSymbol": "PHGDH",
      "hgvs": [
        "XM_011541227.2:c.858del"
      ],
      "proteinEffect": {
        "hgvs": "XP_011539529.1:p.Ile287SerfsTer?",
        "hgvsWellDefined": "XP_011539529.1:p.[Ile287_Gly291delinsSerTrpThrLys;Leu293_Gln298delinsProCysSerGlyProCys;Gly300_Ala306delinsLeuAlaSerValProGly;Asp308_Pro315delinsHisTrpThrCysLeuArgLysSer;Arg316_Asp317insHis]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS554357"
    },
    {
      "coordinates": [
        {
          "allele": "",
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          "referenceAllele": "G",
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      ],
      "gene": "http://reg.genome.network/gene/GN008923",
      "geneNCBI_id": 26227,
      "geneSymbol": "PHGDH",
      "hgvs": [
        "XM_011541228.2:c.825del"
      ],
      "proteinEffect": {
        "hgvs": "XP_011539530.1:p.Ile276SerfsTer?",
        "hgvsWellDefined": "XP_011539530.1:p.[Ile276_Gly280delinsSerTrpThrLys;Leu282_Gln287delinsProCysSerGlyProCys;Gly289_Ala295delinsLeuAlaSerValProGly;Asp297_Pro304delinsHisTrpThrCysLeuArgLysSer;Arg305_Asp306insHis]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS554358"
    },
    {
      "coordinates": [
        {
          "allele": "",
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          "referenceAllele": "G",
          "start": 1043
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      ],
      "gene": "http://reg.genome.network/gene/GN008923",
      "geneNCBI_id": 26227,
      "geneSymbol": "PHGDH",
      "hgvs": [
        "XM_011541231.2:c.420del"
      ],
      "proteinEffect": {
        "hgvs": "XP_011539533.1:p.Ile141SerfsTer?",
        "hgvsWellDefined": "XP_011539533.1:p.[Ile141_Gly145delinsSerTrpThrLys;Leu147_Gln152delinsProCysSerGlyProCys;Gly154_Ala160delinsLeuAlaSerValProGly;Asp162_Pro169delinsHisTrpThrCysLeuArgLysSer;Arg170_Asp171insHis]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS554359"
    },
    {
      "coordinates": [
        {
          "allele": "",
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          "referenceAllele": "G",
          "start": 5905
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      ],
      "gene": "http://reg.genome.network/gene/GN008923",
      "geneNCBI_id": 26227,
      "geneSymbol": "PHGDH",
      "hgvs": [
        "XM_024446338.1:c.825del"
      ],
      "proteinEffect": {
        "hgvs": "XP_024302106.1:p.Ile276SerfsTer?",
        "hgvsWellDefined": "XP_024302106.1:p.[Ile276_Gly280delinsSerTrpThrLys;Leu282_Gln287delinsProCysSerGlyProCys;Gly289_Ala295delinsLeuAlaSerValProGly;Asp297_Pro304delinsHisTrpThrCysLeuArgLysSer;Arg305_Asp306insHis]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS580004"
    },
    {
      "coordinates": [
        {
          "allele": "",
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          "start": 802
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      ],
      "gene": "http://reg.genome.network/gene/GN008923",
      "geneNCBI_id": 26227,
      "geneSymbol": "PHGDH",
      "hgvs": [
        "NM_006623.4:c.714del"
      ],
      "proteinEffect": {
        "hgvs": "NP_006614.2:p.Ile239SerfsTer?",
        "hgvsWellDefined": "NP_006614.2:p.[Ile239_Gly243delinsSerTrpThrLys;Leu245_Gln250delinsProCysSerGlyProCys;Gly252_Ala258delinsLeuAlaSerValProGly;Asp260_Pro267delinsHisTrpThrCysLeuArgLysSer;Arg268_Asp269insHis]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS696766",
      "MANE": {
        "maneVersion": "1.3",
        "maneStatus": "MANE Select",
        "nucleotide": {
          "Ensembl": {
            "hgvs": "ENST00000641023.2:c.714del"
          },
          "RefSeq": {
            "hgvs": "NM_006623.4:c.714del"
          }
        },
        "protein": {
          "Ensembl": {
            "hgvs": "ENSP00000493175.1:p.Ile239SerfsTer?"
          },
          "RefSeq": {
            "hgvs": "NP_006614.2:p.Ile239SerfsTer?"
          }
        }
      }
    }
  ],
  "type": "nucleotide"
}