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        {
          "allele": "",
          "end": 4579,
          "referenceAllele": "T",
          "start": 4578
        }
      ],
      "gene": "http://reg.genome.network/gene/GN000321",
      "geneNCBI_id": 178,
      "geneSymbol": "AGL",
      "hgvs": [
        "NM_000642.3:c.4456del"
      ],
      "proteinEffect": {
        "hgvs": "NP_000633.2:p.Ser1486ProfsTer18",
        "hgvsWellDefined": "NP_000633.2:p.[Ser1486_His1491delinsProAspIleMetPheIle;Glu1493del;Ser1495Asp;Trp1497_Lys1498delinsLeu;Leu1500_Thr1504delinsLysAspPheGln;Asn1507_Glu1516del]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS662520",
      "MANE": {
        "maneVersion": "1.3",
        "maneStatus": "MANE Select",
        "nucleotide": {
          "Ensembl": {
            "hgvs": "ENST00000361915.8:c.4456del"
          },
          "RefSeq": {
            "hgvs": "NM_000642.3:c.4456del"
          }
        },
        "protein": {
          "Ensembl": {
            "hgvs": "ENSP00000355106.3:p.Ser1486ProfsTer18"
          },
          "RefSeq": {
            "hgvs": "NP_000633.2:p.Ser1486ProfsTer18"
          }
        }
      }
    }
  ],
  "type": "nucleotide"
}