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      "gene": "http://reg.genome.network/gene/GN006547",
      "geneNCBI_id": 3949,
      "geneSymbol": "LDLR",
      "hgvs": [
        "NM_001195798.2:c.905del"
      ],
      "proteinEffect": {
        "hgvs": "NP_001182727.1:p.Cys302SerfsTer?",
        "hgvsWellDefined": "NP_001182727.1:p.[Cys302_Glu308delinsSerGlyThrGlyGlnMetAsn;Ile310Ser;Glu312_Cys313delinsSerAla;Gly314_Thr315insPro;Glu317_Asp331delinsAlaTrpThrThrThrAlaAlaValProThrSerAlaMetThr]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS679343"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 868,
          "referenceAllele": "G",
          "start": 867
        }
      ],
      "gene": "http://reg.genome.network/gene/GN006547",
      "geneNCBI_id": 3949,
      "geneSymbol": "LDLR",
      "hgvs": [
        "NM_001195799.2:c.782del"
      ],
      "proteinEffect": {
        "hgvs": "NP_001182728.1:p.Cys261SerfsTer?",
        "hgvsWellDefined": "NP_001182728.1:p.[Cys261_Glu267delinsSerGlyThrGlyGlnMetAsn;Ile269Ser;Glu271_Cys272delinsSerAla;Gly273_Thr274insPro;Glu276_Asp290delinsAlaTrpThrThrThrAlaAlaValProThrSerAlaMetThr]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS679344"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 487,
          "referenceAllele": "G",
          "start": 486
        }
      ],
      "gene": "http://reg.genome.network/gene/GN006547",
      "geneNCBI_id": 3949,
      "geneSymbol": "LDLR",
      "hgvs": [
        "NM_001195800.2:c.401del"
      ],
      "proteinEffect": {
        "hgvs": "NP_001182729.1:p.Cys134SerfsTer?",
        "hgvsWellDefined": "NP_001182729.1:p.[Cys134_Glu140delinsSerGlyThrGlyGlnMetAsn;Ile142Ser;Glu144_Cys145delinsSerAla;Gly146_Thr147insPro;Glu149_Asp163delinsAlaTrpThrThrThrAlaAlaValProThrSerAlaMetThr]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS679345"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 610,
          "referenceAllele": "G",
          "start": 609
        }
      ],
      "gene": "http://reg.genome.network/gene/GN006547",
      "geneNCBI_id": 3949,
      "geneSymbol": "LDLR",
      "hgvs": [
        "NM_001195803.2:c.524del"
      ],
      "proteinEffect": {
        "hgvs": "NP_001182732.1:p.Cys175SerfsTer?",
        "hgvsWellDefined": "NP_001182732.1:p.[Cys175_Glu181delinsSerGlyThrGlyGlnMetAsn;Ile183Ser;Glu185_Cys186delinsSerAla;Gly187_Thr188insPro;Glu190_Asp204delinsAlaTrpThrThrThrAlaAlaValProThrSerAlaMetThr]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS679346"
    }
  ],
  "type": "nucleotide"
}