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      "referenceSequence": "http://reg.genome.network/refseq/RS541252"
    },
    {
      "coordinates": [
        {
          "allele": "CTTA",
          "end": 1513,
          "referenceAllele": "",
          "start": 1513
        }
      ],
      "gene": "http://reg.genome.network/gene/GN002343",
      "geneNCBI_id": 23418,
      "geneSymbol": "CRB1",
      "hgvs": [
        "XM_017000851.1:c.769_770insCTTA"
      ],
      "proteinEffect": {
        "hgvs": "XP_016856340.1:p.Leu257ProfsTer14",
        "hgvsWellDefined": "XP_016856340.1:p.[Leu257_Gly259delinsPro;Ile261_His262delinsLysTrp;Ser264_Gln270delinsHis;Lys272_Val273del;Leu275_Phe276del;Ser278_His279del;Thr281del;Asp283del;Glu285_Trp286delinsGln]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS557131"
    },
    {
      "coordinates": [
        {
          "allele": "CTTA",
          "end": 1746,
          "referenceAllele": "",
          "start": 1746
        }
      ],
      "gene": "http://reg.genome.network/gene/GN002343",
      "geneNCBI_id": 23418,
      "geneSymbol": "CRB1",
      "hgvs": [
        "XM_017000852.1:c.1612_1613insCTTA"
      ],
      "proteinEffect": {
        "hgvs": "XP_016856341.1:p.Leu538ProfsTer14",
        "hgvsWellDefined": "XP_016856341.1:p.[Leu538_Gly540delinsPro;Ile542_His543delinsLysTrp;Ser545_Gln551delinsHis;Lys553_Val554del;Leu556_Phe557del;Ser559_His560del;Thr562del;Asp564del;Glu566_Trp567delinsGln]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS557132"
    },
    {
      "coordinates": [
        {
          "allele": "CTTA",
          "end": 1773,
          "referenceAllele": "",
          "start": 1773
        }
      ],
      "gene": "http://reg.genome.network/gene/GN002343",
      "geneNCBI_id": 23418,
      "geneSymbol": "CRB1",
      "hgvs": [
        "NM_201253.3:c.1612_1613insCTTA"
      ],
      "proteinEffect": {
        "hgvs": "NP_957705.1:p.Leu538ProfsTer14",
        "hgvsWellDefined": "NP_957705.1:p.[Leu538_Gly540delinsPro;Ile542_His543delinsLysTrp;Ser545_Gln551delinsHis;Lys553_Val554del;Leu556_Phe557del;Ser559_His560del;Thr562del;Asp564del;Glu566_Trp567delinsGln]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS673211",
      "MANE": {
        "maneVersion": "1.3",
        "maneStatus": "MANE Select",
        "nucleotide": {
          "Ensembl": {
            "hgvs": "ENST00000367400.8:c.1612_1613insCTTA"
          },
          "RefSeq": {
            "hgvs": "NM_201253.3:c.1612_1613insCTTA"
          }
        },
        "protein": {
          "Ensembl": {
            "hgvs": "ENSP00000356370.3:p.Leu538ProfsTer14"
          },
          "RefSeq": {
            "hgvs": "NP_957705.1:p.Leu538ProfsTer14"
          }
        }
      }
    },
    {
      "coordinates": [
        {
          "allele": "CTTA",
          "end": 1437,
          "referenceAllele": "",
          "start": 1437
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      ],
      "gene": "http://reg.genome.network/gene/GN002343",
      "geneNCBI_id": 23418,
      "geneSymbol": "CRB1",
      "hgvs": [
        "NM_001193640.2:c.1276_1277insCTTA"
      ],
      "proteinEffect": {
        "hgvs": "NP_001180569.1:p.Leu426ProfsTer14",
        "hgvsWellDefined": "NP_001180569.1:p.[Leu426_Gly428delinsPro;Ile430_His431delinsLysTrp;Ser433_Gln439delinsHis;Lys441_Val442del;Leu444_Phe445del;Ser447_His448del;Thr450del;Asp452del;Glu454_Trp455delinsGln]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS679252"
    },
    {
      "coordinates": [
        {
          "allele": "CTTA",
          "end": 1702,
          "referenceAllele": "",
          "start": 1702
        }
      ],
      "gene": "http://reg.genome.network/gene/GN002343",
      "geneNCBI_id": 23418,
      "geneSymbol": "CRB1",
      "hgvs": [
        "NM_001257965.2:c.1405_1406insCTTA"
      ],
      "proteinEffect": {
        "hgvs": "NP_001244894.1:p.Leu469ProfsTer14",
        "hgvsWellDefined": "NP_001244894.1:p.[Leu469_Gly471delinsPro;Ile473_His474delinsLysTrp;Ser476_Gln482delinsHis;Lys484_Val485del;Leu487_Phe488del;Ser490_His491del;Thr493del;Asp495del;Glu497_Trp498delinsGln]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS680747"
    },
    {
      "coordinates": [
        {
          "allele": "CTTA",
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          "referenceAllele": "",
          "start": 1773
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      ],
      "gene": "http://reg.genome.network/gene/GN002343",
      "geneNCBI_id": 23418,
      "geneSymbol": "CRB1",
      "hgvs": [
        "NR_047563.2:n.1773_1774insCTTA"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS702513"
    },
    {
      "coordinates": [
        {
          "allele": "CTTA",
          "end": 1773,
          "referenceAllele": "",
          "start": 1773
        }
      ],
      "gene": "http://reg.genome.network/gene/GN002343",
      "geneNCBI_id": 23418,
      "geneSymbol": "CRB1",
      "hgvs": [
        "NR_047564.2:n.1773_1774insCTTA"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS702514"
    },
    {
      "coordinates": [
        {
          "allele": "CTTA",
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          "referenceAllele": "",
          "start": 1773
        }
      ],
      "gene": "http://reg.genome.network/gene/GN002343",
      "geneNCBI_id": 23418,
      "geneSymbol": "CRB1",
      "hgvs": [
        "NM_001257966.2:c.1612_1613insCTTA"
      ],
      "proteinEffect": {
        "hgvs": "NP_001244895.1:p.Leu538ProfsTer14",
        "hgvsWellDefined": "NP_001244895.1:p.[Leu538_Gly540delinsPro;Ile542_His543delinsLysTrp;Ser545_Gln551delinsHis;Lys553_Val554del;Leu556_Phe557del;Ser559_His560del;Thr562del;Asp564del;Glu566_Trp567delinsGln]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS714892"
    }
  ],
  "type": "nucleotide"
}