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      "coordinates": [
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        "hgvsWellDefined": "XP_006717989.1:p.Tyr300_Val388delinsLeuValLeuThrLeuThrLysAsnAspLeuAspLysAlaAsnLysAspLysAlaAsnArgTyrPheSerProAsnPheLysValLysLeuTyrPheThrLysThrValGluGluProSerAsnProGluAlaSerSerSerThrSerValThrProAspValSerAspAsnGluProAspHisTyrArgTyrSerAspThrThrAspSerAspProGluAsnGluProPheAspGluAspGlnHisThrGlnIleThrLysValTer"
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        "hgvsWellDefined": "XP_011538284.1:p.Tyr283_Val371delinsLeuValLeuThrLeuThrLysAsnAspLeuAspLysAlaAsnLysAspLysAlaAsnArgTyrPheSerProAsnPheLysValLysLeuTyrPheThrLysThrValGluGluProSerAsnProGluAlaSerSerSerThrSerValThrProAspValSerAspAsnGluProAspHisTyrArgTyrSerAspThrThrAspSerAspProGluAsnGluProPheAspGluAspGlnHisThrGlnIleThrLysValTer"
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      "referenceSequence": "http://reg.genome.network/refseq/RS139424"
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    {
      "@id": "http://reg.genome.network/allele/PA645508435",
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      },
      "referenceSequence": "http://reg.genome.network/refseq/RS662397"
    },
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      "gene": "http://reg.genome.network/gene/GN009588",
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        "hgvsWellDefined": "NP_001291646.4:p.Tyr488_Val576delinsLeuValLeuThrLeuThrLysAsnAspLeuAspLysAlaAsnLysAspLysAlaAsnArgTyrPheSerProAsnPheLysValLysLeuTyrPheThrLysThrValGluGluProSerAsnProGluAlaSerSerSerThrSerValThrProAspValSerAspAsnGluProAspHisTyrArgTyrSerAspThrThrAspSerAspProGluAsnGluProPheAspGluAspGlnHisThrGlnIleThrLysValTer"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS664314"
    },
    {
      "@id": "http://reg.genome.network/allele/PA2826897342",
      "coordinates": [
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          "allele": "A",
          "end": 1903,
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          "start": 1902
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      ],
      "gene": "http://reg.genome.network/gene/GN009588",
      "geneNCBI_id": 5728,
      "geneSymbol": "PTEN",
      "hgvs": [
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      "proteinEffect": {
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        "hgvsWellDefined": "NP_001291647.1:p.Tyr118_Val206delinsLeuValLeuThrLeuThrLysAsnAspLeuAspLysAlaAsnLysAspLysAlaAsnArgTyrPheSerProAsnPheLysValLysLeuTyrPheThrLysThrValGluGluProSerAsnProGluAlaSerSerSerThrSerValThrProAspValSerAspAsnGluProAspHisTyrArgTyrSerAspThrThrAspSerAspProGluAsnGluProPheAspGluAspGlnHisThrGlnIleThrLysValTer"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS664315"
    },
    {
      "@id": "http://reg.genome.network/allele/PA645508435",
      "coordinates": [
        {
          "allele": "A",
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      ],
      "gene": "http://reg.genome.network/gene/GN009588",
      "geneNCBI_id": 5728,
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      "hgvs": [
        "NM_000314.8:c.945T>A"
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        "hgvsWellDefined": "NP_000305.3:p.Tyr315_Val403delinsLeuValLeuThrLeuThrLysAsnAspLeuAspLysAlaAsnLysAspLysAlaAsnArgTyrPheSerProAsnPheLysValLysLeuTyrPheThrLysThrValGluGluProSerAsnProGluAlaSerSerSerThrSerValThrProAspValSerAspAsnGluProAspHisTyrArgTyrSerAspThrThrAspSerAspProGluAsnGluProPheAspGluAspGlnHisThrGlnIleThrLysValTer"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS674788",
      "MANE": {
        "maneVersion": "1.3",
        "maneStatus": "MANE Select",
        "nucleotide": {
          "Ensembl": {
            "hgvs": "ENST00000371953.8:c.945T>A"
          },
          "RefSeq": {
            "hgvs": "NM_000314.8:c.945T>A"
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        },
        "protein": {
          "Ensembl": {
            "hgvs": "ENSP00000361021.3:p.Tyr315Ter"
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            "hgvs": "NP_000305.3:p.Tyr315Ter"
          }
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    }
  ],
  "type": "nucleotide"
}