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            "hgvs": "NM_000061.3:c.141+11C>T"
          }
        },
        "protein": {
          "Ensembl": {
            "hgvs": "ENSP00000308176.8:n.141+11C>T"
          },
          "RefSeq": {
            "hgvs": "NP_000052.1:n.141+11C>T"
          }
        }
      }
    },
    {
      "coordinates": [
        {
          "allele": "T",
          "end": 490,
          "endIntronDirection": "+",
          "endIntronOffset": 11,
          "referenceAllele": "C",
          "start": 490,
          "startIntronDirection": "+",
          "startIntronOffset": 10
        }
      ],
      "gene": "http://reg.genome.network/gene/GN001133",
      "geneNCBI_id": 695,
      "geneSymbol": "BTK",
      "hgvs": [
        "NM_001287344.2:c.243+11C>T"
      ],
      "proteinEffect": {
        "hgvs": "NP_001274273.1:n.243+11C>T"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS716364"
    },
    {
      "coordinates": [
        {
          "allele": "T",
          "end": 466,
          "endIntronDirection": "+",
          "endIntronOffset": 11,
          "referenceAllele": "C",
          "start": 466,
          "startIntronDirection": "+",
          "startIntronOffset": 10
        }
      ],
      "gene": "http://reg.genome.network/gene/GN001133",
      "geneNCBI_id": 695,
      "geneSymbol": "BTK",
      "hgvs": [
        "NM_001287345.2:c.141+11C>T"
      ],
      "proteinEffect": {
        "hgvs": "NP_001274274.1:n.141+11C>T"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS716365"
    }
  ],
  "type": "nucleotide"
}