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      "proteinEffect": {
        "hgvs": "NP_000242.1:p.Phe366LeufsTer23",
        "hgvsWellDefined": "NP_000242.1:p.[Phe366_Leu372delinsLeuCysArgArgCys;Gln374_Glu378delinsIleGluAla;Leu380_Leu381delinsPheThr;Pro385_Gln395delinsThrSerSerIleProArgSer]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS674763",
      "MANE": {
        "maneVersion": "1.3",
        "maneStatus": "MANE Select",
        "nucleotide": {
          "Ensembl": {
            "hgvs": "ENST00000233146.7:c.1097_1098insA"
          },
          "RefSeq": {
            "hgvs": "NM_000251.3:c.1097_1098insA"
          }
        },
        "protein": {
          "Ensembl": {
            "hgvs": "ENSP00000233146.2:p.Phe366LeufsTer23"
          },
          "RefSeq": {
            "hgvs": "NP_000242.1:p.Phe366LeufsTer23"
          }
        }
      }
    }
  ],
  "type": "nucleotide"
}