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      },
      "referenceSequence": "http://reg.genome.network/refseq/RS678218"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1321,
          "referenceAllele": "C",
          "start": 1320
        }
      ],
      "gene": "http://reg.genome.network/gene/GN012362",
      "geneNCBI_id": 7248,
      "geneSymbol": "TSC1",
      "hgvs": [
        "NM_001162427.2:c.1104del"
      ],
      "proteinEffect": {
        "hgvs": "NP_001155899.1:p.Arg369GlyfsTer20",
        "hgvsWellDefined": "NP_001155899.1:p.[Pro368_Arg369insGly;Glu371Arg;Arg373_Cys380delinsTrpIle;His382_Arg383del;His385Asp;Leu387_Asn389delinsValTyrThr;Arg391_Gly398delinsAsnThrIlePhe]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS678219"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1370,
          "referenceAllele": "C",
          "start": 1369
        }
      ],
      "gene": "http://reg.genome.network/gene/GN012362",
      "geneNCBI_id": 7248,
      "geneSymbol": "TSC1",
      "hgvs": [
        "NM_001362177.2:c.894del"
      ],
      "proteinEffect": {
        "hgvs": "NP_001349106.1:p.Arg299GlyfsTer20",
        "hgvsWellDefined": "NP_001349106.1:p.[Pro298_Arg299insGly;Glu301Arg;Arg303_Cys310delinsTrpIle;His312_Arg313del;His315Asp;Leu317_Asn319delinsValTyrThr;Arg321_Gly328delinsAsnThrIlePhe]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS690502"
    }
  ],
  "type": "nucleotide"
}