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        "hgvsWellDefined": "XP_011538283.1:p.[Lys267_Asp268delinsArgThr;Met270Cys;His272_Asn276del;Phe279_Pro281del;Pro283_Cys296del]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS106931"
    },
    {
      "coordinates": [
        {
          "allele": "",
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          "referenceAllele": "A",
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      ],
      "gene": "http://reg.genome.network/gene/GN009588",
      "geneNCBI_id": 5728,
      "geneSymbol": "PTEN",
      "hgvs": [
        "XM_011539982.1:c.704del"
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      "proteinEffect": {
        "hgvs": "XP_011538284.1:p.Lys235ArgfsTer9",
        "hgvsWellDefined": "XP_011538284.1:p.[Lys235_Asp236delinsArgThr;Met238Cys;His240_Asn244del;Phe247_Pro249del;Pro251_Cys264del]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS106932"
    },
    {
      "coordinates": [
        {
          "allele": "",
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          "referenceAllele": "A",
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      "gene": "http://reg.genome.network/gene/GN009588",
      "geneNCBI_id": 5728,
      "geneSymbol": "PTEN",
      "hgvs": [
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      "referenceSequence": "http://reg.genome.network/refseq/RS139424"
    },
    {
      "coordinates": [
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          "allele": "",
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      "gene": "http://reg.genome.network/gene/GN009588",
      "geneNCBI_id": 5728,
      "geneSymbol": "PTEN",
      "hgvs": [
        "NM_000314.7:c.800del"
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      "proteinEffect": {
        "hgvs": "NP_000305.3:p.Lys267ArgfsTer9",
        "hgvsWellDefined": "NP_000305.3:p.[Lys267_Asp268delinsArgThr;Met270Cys;His272_Asn276del;Phe279_Pro281del;Pro283_Cys296del]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS662397"
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      "gene": "http://reg.genome.network/gene/GN009588",
      "geneNCBI_id": 5728,
      "geneSymbol": "PTEN",
      "hgvs": [
        "NM_001304717.5:c.1319del"
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      "proteinEffect": {
        "hgvs": "NP_001291646.4:p.Lys440ArgfsTer9",
        "hgvsWellDefined": "NP_001291646.4:p.[Lys440_Asp441delinsArgThr;Met443Cys;His445_Asn449del;Phe452_Pro454del;Pro456_Cys469del]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS664314"
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    {
      "coordinates": [
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      "gene": "http://reg.genome.network/gene/GN009588",
      "geneNCBI_id": 5728,
      "geneSymbol": "PTEN",
      "hgvs": [
        "NM_001304718.2:c.209del"
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      "proteinEffect": {
        "hgvs": "NP_001291647.1:p.Lys70ArgfsTer9",
        "hgvsWellDefined": "NP_001291647.1:p.[Lys70_Asp71delinsArgThr;Met73Cys;His75_Asn79del;Phe82_Pro84del;Pro86_Cys99del]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS664315"
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    {
      "coordinates": [
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      "gene": "http://reg.genome.network/gene/GN009588",
      "geneNCBI_id": 5728,
      "geneSymbol": "PTEN",
      "hgvs": [
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      "proteinEffect": {
        "hgvs": "NP_000305.3:p.Lys267ArgfsTer9",
        "hgvsWellDefined": "NP_000305.3:p.[Lys267_Asp268delinsArgThr;Met270Cys;His272_Asn276del;Phe279_Pro281del;Pro283_Cys296del]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS674788",
      "MANE": {
        "maneVersion": "1.3",
        "maneStatus": "MANE Select",
        "nucleotide": {
          "Ensembl": {
            "hgvs": "ENST00000371953.8:c.800del"
          },
          "RefSeq": {
            "hgvs": "NM_000314.8:c.800del"
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        "protein": {
          "Ensembl": {
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    }
  ],
  "type": "nucleotide"
}