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      },
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    },
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        {
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          "end": 60,
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      ],
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      },
      "referenceSequence": "http://reg.genome.network/refseq/RS025775"
    },
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          "end": 1778,
          "referenceAllele": "C",
          "start": 1777
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      ],
      "gene": "http://reg.genome.network/gene/GN009588",
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      "geneSymbol": "PTEN",
      "hgvs": [
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      "proteinEffect": {
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        "hgvsWellDefined": "NP_001291647.1:p.Cys14_Val206delinsAsnProGlnPheValValCysGlnLeuLysValLysIleTyrSerSerAsnSerGlyProThrArgArgGluAspLysPheMetTyrPheGluPheProGlnProLeuProValCysGlyAspIleLysValGluPhePheHisLysGlnAsnLysMetLeuLysLysAspLysMetPheHisPheTrpValAsnThrPhePheIleProGlyProGluGluThrSerGluLysValGluAsnGlySerLeuCysAspGlnGluIleAspSerIleCysSerIleGluArgAlaAspAsnAspLysGluTyrLeuValLeuThrLeuThrLysAsnAspLeuAspLysAlaAsnLysAspLysAlaAsnArgTyrPheSerProAsnPheLysValLysLeuTyrPheThrLysThrValGluGluProSerAsnProGluAlaSerSerSerThrSerValThrProAspValSerAspAsnGluProAspHisTyrArgTyrSerAspThrThrAspSerAspProGluAsnGluProPheAspGluAspGlnHisThrGlnIleThrLysValTer"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS025776"
    },
    {
      "coordinates": [
        {
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          "start": 1299
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      ],
      "gene": "http://reg.genome.network/gene/GN009588",
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      "proteinEffect": {
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        "hgvsWellDefined": "XP_006717989.1:p.Cys196_Val388delinsAsnProGlnPheValValCysGlnLeuLysValLysIleTyrSerSerAsnSerGlyProThrArgArgGluAspLysPheMetTyrPheGluPheProGlnProLeuProValCysGlyAspIleLysValGluPhePheHisLysGlnAsnLysMetLeuLysLysAspLysMetPheHisPheTrpValAsnThrPhePheIleProGlyProGluGluThrSerGluLysValGluAsnGlySerLeuCysAspGlnGluIleAspSerIleCysSerIleGluArgAlaAspAsnAspLysGluTyrLeuValLeuThrLeuThrLysAsnAspLeuAspLysAlaAsnLysAspLysAlaAsnArgTyrPheSerProAsnPheLysValLysLeuTyrPheThrLysThrValGluGluProSerAsnProGluAlaSerSerSerThrSerValThrProAspValSerAspAsnGluProAspHisTyrArgTyrSerAspThrThrAspSerAspProGluAsnGluProPheAspGluAspGlnHisThrGlnIleThrLysValTer"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS072385"
    },
    {
      "coordinates": [
        {
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          "end": 1345,
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      "proteinEffect": {
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        "hgvsWellDefined": "XP_011538283.1:p.Cys211_Arg344delinsAsnProGlnPheValValCysGlnLeuLysValLysIleTyrSerSerAsnSerGlyProThrArgArgGluAspLysPheMetTyrPheGluPheProGlnProLeuProValCysGlyAspIleLysValGluPhePheHisLysGlnAsnLysMetLeuLysLysAspLysMetPheHisPheTrpValAsnThrPhePheIleProGlyProGluGluThrSerGluLysValGluAsnGlySerLeuCysAspGlnGluIleAspSerIleCysSerIleGluArgAlaAspAsnAspLysGluTyrLeuValLeuThrLeuThrLysAsnAspLeuAspLysAlaAsnLysAspLysAlaAsnArgTyrPheSerProAsnPheLysGlnArgTer"
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      "referenceSequence": "http://reg.genome.network/refseq/RS106931"
    },
    {
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        }
      ],
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      },
      "referenceSequence": "http://reg.genome.network/refseq/RS106932"
    },
    {
      "coordinates": [
        {
          "allele": "A",
          "end": 1204,
          "endIntronDirection": "-",
          "endIntronOffset": 5594,
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          "start": 1204,
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          "startIntronOffset": 5595
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      "referenceSequence": "http://reg.genome.network/refseq/RS139424"
    },
    {
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      ],
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      },
      "referenceSequence": "http://reg.genome.network/refseq/RS662397"
    },
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      "@id": "http://reg.genome.network/allele/PA916019982",
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        "hgvsWellDefined": "NP_001291646.4:p.Cys384_Val576delinsAsnProGlnPheValValCysGlnLeuLysValLysIleTyrSerSerAsnSerGlyProThrArgArgGluAspLysPheMetTyrPheGluPheProGlnProLeuProValCysGlyAspIleLysValGluPhePheHisLysGlnAsnLysMetLeuLysLysAspLysMetPheHisPheTrpValAsnThrPhePheIleProGlyProGluGluThrSerGluLysValGluAsnGlySerLeuCysAspGlnGluIleAspSerIleCysSerIleGluArgAlaAspAsnAspLysGluTyrLeuValLeuThrLeuThrLysAsnAspLeuAspLysAlaAsnLysAspLysAlaAsnArgTyrPheSerProAsnPheLysValLysLeuTyrPheThrLysThrValGluGluProSerAsnProGluAlaSerSerSerThrSerValThrProAspValSerAspAsnGluProAspHisTyrArgTyrSerAspThrThrAspSerAspProGluAsnGluProPheAspGluAspGlnHisThrGlnIleThrLysValTer"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS664314"
    },
    {
      "@id": "http://reg.genome.network/allele/PA2826897151",
      "coordinates": [
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          "referenceAllele": "C",
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        }
      ],
      "gene": "http://reg.genome.network/gene/GN009588",
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      "geneSymbol": "PTEN",
      "hgvs": [
        "NM_001304718.2:c.42C>A"
      ],
      "proteinEffect": {
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        "hgvsWellDefined": "NP_001291647.1:p.Cys14_Val206delinsAsnProGlnPheValValCysGlnLeuLysValLysIleTyrSerSerAsnSerGlyProThrArgArgGluAspLysPheMetTyrPheGluPheProGlnProLeuProValCysGlyAspIleLysValGluPhePheHisLysGlnAsnLysMetLeuLysLysAspLysMetPheHisPheTrpValAsnThrPhePheIleProGlyProGluGluThrSerGluLysValGluAsnGlySerLeuCysAspGlnGluIleAspSerIleCysSerIleGluArgAlaAspAsnAspLysGluTyrLeuValLeuThrLeuThrLysAsnAspLeuAspLysAlaAsnLysAspLysAlaAsnArgTyrPheSerProAsnPheLysValLysLeuTyrPheThrLysThrValGluGluProSerAsnProGluAlaSerSerSerThrSerValThrProAspValSerAspAsnGluProAspHisTyrArgTyrSerAspThrThrAspSerAspProGluAsnGluProPheAspGluAspGlnHisThrGlnIleThrLysValTer"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS664315"
    },
    {
      "@id": "http://reg.genome.network/allele/PA119104",
      "coordinates": [
        {
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          "end": 1478,
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        }
      ],
      "gene": "http://reg.genome.network/gene/GN009588",
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      "hgvs": [
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      "proteinEffect": {
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        "hgvsWellDefined": "NP_000305.3:p.Cys211_Val403delinsAsnProGlnPheValValCysGlnLeuLysValLysIleTyrSerSerAsnSerGlyProThrArgArgGluAspLysPheMetTyrPheGluPheProGlnProLeuProValCysGlyAspIleLysValGluPhePheHisLysGlnAsnLysMetLeuLysLysAspLysMetPheHisPheTrpValAsnThrPhePheIleProGlyProGluGluThrSerGluLysValGluAsnGlySerLeuCysAspGlnGluIleAspSerIleCysSerIleGluArgAlaAspAsnAspLysGluTyrLeuValLeuThrLeuThrLysAsnAspLeuAspLysAlaAsnLysAspLysAlaAsnArgTyrPheSerProAsnPheLysValLysLeuTyrPheThrLysThrValGluGluProSerAsnProGluAlaSerSerSerThrSerValThrProAspValSerAspAsnGluProAspHisTyrArgTyrSerAspThrThrAspSerAspProGluAsnGluProPheAspGluAspGlnHisThrGlnIleThrLysValTer"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS674788",
      "MANE": {
        "maneVersion": "1.3",
        "maneStatus": "MANE Select",
        "nucleotide": {
          "Ensembl": {
            "hgvs": "ENST00000371953.8:c.633C>A"
          },
          "RefSeq": {
            "hgvs": "NM_000314.8:c.633C>A"
          }
        },
        "protein": {
          "Ensembl": {
            "hgvs": "ENSP00000361021.3:p.Cys211Ter"
          },
          "RefSeq": {
            "hgvs": "NP_000305.3:p.Cys211Ter"
          }
        }
      }
    }
  ],
  "type": "nucleotide"
}