Canonical Allele Identifier: CA369542735

Gene: BRAF

Linked Data

• gnomAD v4: 7-140753282-A-T
• MyVariant Identifiers: chr7:g.140453082A>T (hg19) ; chr7:g.140753282A>T (hg38)

Genomic Alleles

HGVS	Genome Assembly
NC_000007.14:g.140753282A>T , CM000669.2:g.140753282A>T	GRCh38
NC_000007.13:g.140453082A>T , CM000669.1:g.140453082A>T	GRCh37
NC_000007.12:g.140099551A>T	NCBI36
NG_007873.3:g.176483T>A , LRG_299:g.176483T>A

Transcript Alleles

HGVS	Amino-acid change
ENST00000646891.2:c.1853T>A MANE Select	ENSP00000493543.1:p.Leu618Ter
ENST00000288602.11:c.1973T>A	ENSP00000288602.7:p.Leu658Ter
ENST00000479537.6:c.523T>A
ENST00000496384.7:c.1853T>A	ENSP00000419060.2:p.Leu618Ter
ENST00000497784.2:c.*1303T>A	ENSP00000420119.2:n.*1303T>A
ENST00000642228.1:c.*931T>A	ENSP00000493678.1:n.*931T>A
ENST00000642875.1:n.1259-3864T>A
ENST00000644120.1:n.2243T>A
ENST00000644650.1:c.949T>A
ENST00000644905.1:n.2735T>A
ENST00000644969.2:c.1973T>A MANE Plus Clinical	ENSP00000496776.1:p.Leu658Ter
ENST00000646730.1:c.*429T>A	ENSP00000494784.1:n.*429T>A
ENST00000646891.1:c.1853T>A	ENSP00000493543.1:p.Leu618Ter
ENST00000647434.1:c.738-3864T>A	ENSP00000495132.1:n.738-3864T>A
ENST00000288602.10:c.1853T>A	ENSP00000288602.6:p.Leu618Ter
ENST00000479537.5:c.137T>A	ENSP00000418033.1:p.Leu46Ter
ENST00000496384.6:c.676T>A
ENST00000497784.1:c.1888T>A	ENSP00000420119.1:n.1888T>A
NM_004333.4:c.1853T>A , LRG_299t1:c.1853T>A	NP_004324.2:p.Leu618Ter
XM_005250045.1:c.1853T>A	XP_005250102.1:p.Leu618Ter
XM_005250046.1:c.1853T>A	XP_005250103.1:p.Leu618Ter
XM_011516529.1:c.1853T>A	XP_011514831.1:p.Leu618Ter
XM_011516530.1:c.1695-3864T>A	XP_011514832.1:n.1695-3864T>A
XR_242190.1:n.1861T>A
XR_927520.1:n.1861T>A
XR_927521.1:n.1861T>A
XR_927522.1:n.1703-3864T>A
XR_927523.1:n.1703-3864T>A
NM_001354609.1:c.1853T>A	NP_001341538.1:p.Leu618Ter
NM_004333.5:c.1853T>A	NP_004324.2:p.Leu618Ter
NR_148928.1:n.2951T>A
XM_017012558.1:c.1973T>A	XP_016868047.1:p.Leu658Ter
XM_017012559.1:c.1973T>A	XP_016868048.1:p.Leu658Ter
XR_001744857.1:n.1981T>A
XR_001744858.1:n.1823-3864T>A
NM_001354609.2:c.1853T>A	NP_001341538.1:p.Leu618Ter
NM_001374244.1:c.1973T>A	NP_001361173.1:p.Leu658Ter
NM_001374258.1:c.1973T>A MANE Plus Clinical	NP_001361187.1:p.Leu658Ter
NM_004333.6:c.1853T>A MANE Select	NP_004324.2:p.Leu618Ter
NM_001378467.1:c.1862T>A	NP_001365396.1:p.Leu621Ter
NM_001378468.1:c.1853T>A	NP_001365397.1:p.Leu618Ter
NM_001378469.1:c.1787T>A	NP_001365398.1:p.Leu596Ter
NM_001378470.1:c.1751T>A	NP_001365399.1:p.Leu584Ter
NM_001378471.1:c.1742T>A	NP_001365400.1:p.Leu581Ter
NM_001378472.1:c.1697T>A	NP_001365401.1:p.Leu566Ter
NM_001378473.1:c.1697T>A	NP_001365402.1:p.Leu566Ter
NM_001378474.1:c.1853T>A	NP_001365403.1:p.Leu618Ter
NM_001378475.1:c.1589T>A	NP_001365404.1:p.Leu530Ter