Canonical Allele Identifier: CA352054021
Gene: MLH1 HGNC NCBI

Linked Data

dbSNP Id: rs2125886617

Genomic Alleles

HGVS Genome Assembly
NC_000003.12:g.37025982A>T , CM000665.2:g.37025982A>T GRCh38
NC_000003.11:g.37067473A>T , CM000665.1:g.37067473A>T GRCh37
NC_000003.10:g.37042477A>T NCBI36
NG_007109.2:g.37633A>T , LRG_216:g.37633A>T

Transcript Alleles

HGVS Amino-acid change
ENST00000413740.2:c.1384A>T ENSP00000416476.2:p.Arg462Ter
ENST00000429117.6:c.1090A>T ENSP00000407019.2:p.Arg364Ter
ENST00000450420.6:c.1384A>T ENSP00000393006.2:p.Arg462Ter
ENST00000456676.7:c.1384A>T ENSP00000416687.3:p.Arg462Ter
ENST00000458009.6:c.*285A>T ENSP00000411066.2:n.*285A>T
ENST00000492474.6:c.661A>T ENSP00000518393.1:p.Arg221Ter
ENST00000616768.6:c.1384A>T ENSP00000480669.3:p.Arg462Ter
ENST00000673673.2:c.1384A>T ENSP00000500979.2:p.Arg462Ter
ENST00000231790.8:c.1384A>T MANE Select ENSP00000231790.3:p.Arg462Ter
ENST00000413212.2:c.*302A>T ENSP00000400844.2:n.*302A>T
ENST00000432299.6:c.*1216A>T ENSP00000416783.1:n.*1216A>T
ENST00000441265.6:c.661A>T ENSP00000398392.2:p.Arg221Ter
ENST00000442249.6:n.1192A>T
ENST00000447829.6:c.*495A>T ENSP00000399329.2:n.*495A>T
ENST00000539477.6:c.661A>T ENSP00000443665.1:p.Arg221Ter
ENST00000616768.5:c.421A>T ENSP00000480669.2:p.Arg141Ter
ENST00000673673.1:c.1337A>T
ENST00000673713.1:n.1508A>T
ENST00000673715.1:c.1384A>T ENSP00000501301.1:p.Arg462Ter
ENST00000673889.1:n.766A>T
ENST00000673897.1:c.*1176A>T ENSP00000501109.1:n.*1176A>T
ENST00000673899.1:c.678-2802A>T ENSP00000501030.1:n.678-2802A>T
ENST00000673947.1:c.*1524A>T ENSP00000501304.1:n.*1524A>T
ENST00000673972.1:c.*1262A>T ENSP00000501281.1:n.*1262A>T
ENST00000673990.1:n.1275A>T
ENST00000674019.1:c.661A>T ENSP00000501081.1:p.Arg221Ter
ENST00000674107.1:n.1232A>T
ENST00000674111.1:c.1384A>T ENSP00000501162.1:p.Arg462Ter
ENST00000231790.6:c.1384A>T ENSP00000231790.2:p.Arg462Ter
ENST00000413212.1:c.459A>T
ENST00000413740.1:c.7A>T ENSP00000416476.1:p.Arg3Ter
ENST00000435176.5:c.1090A>T ENSP00000402564.1:p.Arg364Ter
ENST00000450420.5:c.7A>T ENSP00000393006.1:p.Arg3Ter
ENST00000455445.6:c.661A>T ENSP00000398272.2:p.Arg221Ter
ENST00000456676.6:c.1359A>T
ENST00000458009.5:c.571A>T
ENST00000458205.6:c.661A>T ENSP00000402667.2:p.Arg221Ter
ENST00000536378.5:c.661A>T ENSP00000444286.2:p.Arg221Ter
ENST00000539477.5:c.661A>T ENSP00000443665.1:p.Arg221Ter
ENST00000616768.4:c.152A>T
NM_000249.3:c.1384A>T , LRG_216t1:c.1384A>T NP_000240.1:p.Arg462Ter
NM_001167617.1:c.1090A>T NP_001161089.1:p.Arg364Ter
NM_001167618.1:c.661A>T NP_001161090.1:p.Arg221Ter
NM_001167619.1:c.661A>T NP_001161091.1:p.Arg221Ter
NM_001258271.1:c.1384A>T NP_001245200.1:p.Arg462Ter
NM_001258273.1:c.661A>T NP_001245202.1:p.Arg221Ter
NM_001258274.1:c.661A>T NP_001245203.1:p.Arg221Ter
XM_005265161.1:c.1177A>T XP_005265218.1:p.Arg393Ter
XM_005265163.1:c.661A>T XP_005265220.1:p.Arg221Ter
XM_005265164.1:c.661A>T XP_005265221.1:p.Arg221Ter
XM_005265166.1:c.361A>T XP_005265223.1:p.Arg121Ter
XM_011533727.1:c.310A>T XP_011532029.1:p.Arg104Ter
NM_001167617.2:c.1090A>T NP_001161089.1:p.Arg364Ter
NM_001167618.2:c.661A>T NP_001161090.1:p.Arg221Ter
NM_001167619.2:c.661A>T NP_001161091.1:p.Arg221Ter
NM_001258274.2:c.661A>T NP_001245203.1:p.Arg221Ter
NM_001354615.1:c.661A>T NP_001341544.1:p.Arg221Ter
NM_001354616.1:c.661A>T NP_001341545.1:p.Arg221Ter
NM_001354617.1:c.661A>T NP_001341546.1:p.Arg221Ter
NM_001354618.1:c.661A>T NP_001341547.1:p.Arg221Ter
NM_001354619.1:c.661A>T NP_001341548.1:p.Arg221Ter
NM_001354620.1:c.1090A>T NP_001341549.1:p.Arg364Ter
NM_001354621.1:c.361A>T NP_001341550.1:p.Arg121Ter
NM_001354622.1:c.361A>T NP_001341551.1:p.Arg121Ter
NM_001354623.1:c.361A>T NP_001341552.1:p.Arg121Ter
NM_001354624.1:c.310A>T NP_001341553.1:p.Arg104Ter
NM_001354625.1:c.310A>T NP_001341554.1:p.Arg104Ter
NM_001354626.1:c.310A>T NP_001341555.1:p.Arg104Ter
NM_001354627.1:c.310A>T NP_001341556.1:p.Arg104Ter
NM_001354628.1:c.1384A>T NP_001341557.1:p.Arg462Ter
NM_001354629.1:c.1285A>T NP_001341558.1:p.Arg429Ter
NM_001354630.1:c.1384A>T NP_001341559.1:p.Arg462Ter
XM_005265161.2:c.1177A>T XP_005265218.1:p.Arg393Ter
XM_017006450.2:c.361A>T XP_016861939.1:p.Arg121Ter
NM_000249.4:c.1384A>T MANE Select NP_000240.1:p.Arg462Ter
NM_001167617.3:c.1090A>T NP_001161089.1:p.Arg364Ter
NM_001167618.3:c.661A>T NP_001161090.1:p.Arg221Ter
NM_001167619.3:c.661A>T NP_001161091.1:p.Arg221Ter
NM_001258271.2:c.1384A>T NP_001245200.1:p.Arg462Ter
NM_001258273.2:c.661A>T NP_001245202.1:p.Arg221Ter
NM_001258274.3:c.661A>T NP_001245203.1:p.Arg221Ter
NM_001354615.2:c.661A>T NP_001341544.1:p.Arg221Ter
NM_001354616.2:c.661A>T NP_001341545.1:p.Arg221Ter
NM_001354617.2:c.661A>T NP_001341546.1:p.Arg221Ter
NM_001354618.2:c.661A>T NP_001341547.1:p.Arg221Ter
NM_001354619.2:c.661A>T NP_001341548.1:p.Arg221Ter
NM_001354620.2:c.1090A>T NP_001341549.1:p.Arg364Ter
NM_001354621.2:c.361A>T NP_001341550.1:p.Arg121Ter
NM_001354622.2:c.361A>T NP_001341551.1:p.Arg121Ter
NM_001354623.2:c.361A>T NP_001341552.1:p.Arg121Ter
NM_001354624.2:c.310A>T NP_001341553.1:p.Arg104Ter
NM_001354625.2:c.310A>T NP_001341554.1:p.Arg104Ter
NM_001354626.2:c.310A>T NP_001341555.1:p.Arg104Ter
NM_001354627.2:c.310A>T NP_001341556.1:p.Arg104Ter
NM_001354628.2:c.1384A>T NP_001341557.1:p.Arg462Ter
NM_001354629.2:c.1285A>T NP_001341558.1:p.Arg429Ter
NM_001354630.2:c.1384A>T NP_001341559.1:p.Arg462Ter